Total Completed Projects
S.No Project Title Unani Formulation
1 Comparison of clinical efficacy and safety of Unani therapy in the form of systemic UNIM-004 & topical UNIM-005 and conventional allopathic therapy in form of PUVA sol and topical mometasone cream in the treatment of clinically stable vitiligo UNIM-004 & topical UNIM-005
2 Redesigning of Dosage form of Majoon-e-Dabeedul Ward and Majoon-e-Falasfa into tablet form along with their Physico-chemical and Pharmacological Evaluation Majoon-e-Dabeedul Ward, Majoon-e-Falasfa
3 A Randomized Clinical trial to Study the Effects of Safoof Muhazzil and orlistat on Biomarkers of Obesity Safoof Muhazzil
4 Experimental studies on the hepato-protective and immune-modulatory effects of Dawa-ul-Kurkum, a polyherbal Unani preparation, and its cellular and molecular mechanisms in rats Dawa-ul-Kurkum
5 Evaluation of the anticancer potential of a unani pharmacopoeial formulation, ‘Dawa-ul-Kurkum’ Dawa-ul-Kurkum
6 Delineating the Anti- Cancer potential and the mechanism of action of Unani medicinal formulation Itrifal-e-Aftimoon in Chronic Myelogenous Leukemia Itrifal-e-Aftimoon
7 Study on Autism in Children using in Unani Herbal Neuro Restorative Supplement and Standard Rehabilitation Therapies Unani Herbal Neuro Restorative Supplement
8 Evaluation of Anti-oxidant and Anticancer Effect of Unani medicine against the Liver cancer : A Preclinical Study Qurs-e-Mafasil Ladeed, Safoof-e-Barang (UNIM-HC-I)
9 Pharmacokinetics, stability and Quality Control Studies on Araqiyat of the Unani Pharmacopoeia of India using HPTLC and GC-MS Araqiyat
10 Formulation & Evaluation of Khamira Banafsha based Comestible Chocolate coated Lozenges/Troches: Prophylactic and Restorative Potential against COVID-19 Infection and associated complications Khamira Banafsha
11 Reverse Pharmacology of Asrin and Dawa Ul Shifa to evaluate their anti-hypertensive efficacy, safety and mechanism of Action. Asrin, Dawa Ul Shifa
12 Phytochemical standardization and evaluation of anti-cancer and immunomodulatory activity of Unani formulation, Itrifal ghudadi Itrifal ghudadi
13 Development of DNA Barcodes for Medicinal Plants used in Unani System of India 100 Unani plants (UPI Vol 1–6)
14 Elucidating the therapeutic potential of a Unani formulation in glaucoma Mameeran, Zanjabeel, Filfil, Dar Til Til, Badyan
15 Investigation on pharmacodynamic and pharmacokinetic interaction of Unani plants Tinospora cordifolia and Eugenia jambolana with hypoglycaemic drug. Tinospora cordifolia, Eugenia jambolana
16 Evaluation of neuro protective potential of Majun Nisyan: A mechanistic study. Majun Nisyan
17 Exploring the Anti-inflammatory Mechanism of Action of Unani Formulation Tiryaq-e- Wabai Tiryaq-e- Wabai
18 Evaluation of Aftimoon (Cuscuta Reflexa Roxb.) Plant and its Seeds on Different Human Cancer (Sartan) Cell Lines. Aftimoon (Cuscuta Reflexa Roxb.)
19 Pharmacological studies on the probable mechanism of action of Khamira Gaozaban Sada (KGS) in the management of Hypertension, involving Quality Control and formulation optimization studies for this age old Unani preparation. Khamira Gaozaban Sada (KGS)
20 Effect of Unani preparations on macrophage polarization and its role in Increased Browning of fat leading to amelioration of insulin resistance. Arq Mako, Arq Qasni

Total Ongoing Projects
S.No Project Title Unani Formulation
1Development of Sugar Free Dosage Forms, Quality Control and Pharmacological Evaluation of Khamira Banafsha, Khamira Aabresham, Laooq-e-Katan, Sharbat Toot Siyah, Laooq Sapistan and Sharbat Zoofa against Covid -19 related disordersKhamira Banafsha, Khamira Aabresham, Laooq-e-Katan, Sharbat Toot Siyah, Laooq Sapistan and Sharbat Zoofa
2Pharmacokinetics, stability and quality control studies on Itrifal’s of the Unani Pharmacopoeia of India (Part 2 Vol.1 & Vol.2) using Chromatographic Analysis by HPTLC and LC-MSItrifal Zamani, Itrifal-e-Muqil, ItrifalMulayan, ItrifalMuqawwiDimagh, Itrifal-e-MuqilMumsik, Itrifal-e-Mushil, Itrifal-e-Sana, Itrifal-e-Zabeeb, Itrifal Zamani
3In vitro Evaluation of Antiviral activity of Unani Drugs and their Green Nano-particles against Dengue Virus.Afsanteen, Gilo, Gul e Nilofer and Khaksi, Habb-e-Papita, Sharbat Anjbarand, Khamira Marwareed
4“Preclinical evaluation of UNIM-401 and UNIM-403 against experimentally induced psoriasis and UNIM-004 and UNIM-005 for their efficacy against experimentally induced vitiligo in mice”UNIM-401 and UNIM-403
UNIM-004 and UNIM-005
5Targeting Alzheimer’s disease by a mixture of Unani plant extract via modulation of human kinaseDried root of Withania somnifera (Asgandh), leaves and stems of Bacopa mon11ieri (Brahmi), fruits of Terminalia chebula (Halela siyah), and oleo-gum resins of Boswellia serrate (Kundur)
6Drug proving studies, mechanistic insight and development of novel drug delivery systems of UNIM H and UNIM R used in the treatment of Arthritis in the Unani system of MedicineUNIM H and UNIM R
7Investigating and validation of the molecular mechanism of Unani medicines in vitro and in vivo for the treatment of Atopic Dermatitis.Barg-e-shahtra, Babchi, Badaam, Sheerin, Tukhme khurfa, and Halela Siyah
8Evaluation of anti tubercular and immune-modulatory activities of Unani Pharmacopoeial formulations (UPF) Qurs Tabasheer Sartani and Arq e Hara Bhara through in vitro and in vivo studies.Qurs Tabasheer Sartani and Arq e Hara Bhara
9Pharmacological activities and pre clinical screening of the promising Unani medicines against hepatic diseases.Saad Koofi (Cyperus rotundus) and Mastagi (Pistacia lentiscus)
10Determination of anti-aging and antioxidant potential of a Unani formulationHabb-e- Asgandh
11Evaluation of immune modulatory and antioxidant potential of a Unani formulationTiryaq-e- Samaniya
12Investigation of hepatoprotective activity of Unani Formulations with emphasis on alleviation of antitubercular drugs' induced hepatotoxicity: Elucidation of molecular mechanismQurs e Afsanteen and Safoof e Jigar
13Redesigning and pharmacological evaluation of some classical Unani formulations with specific reference to immune-modulatory 1activity, safety profile and stability studiesDawa-ul-Kurkum, Halwa Gheekwar, ltrefal Ustkhudus
14Chemotherapeutic effect of a selected Unani Medicine in xenograft mouse model of lung cancerJoshanda-e-Aftimun
15Evaluation of hepato protective efficacy and underlying molecular mechanism of CCRUM formulations, in experimental animal models of Anti-tuberculosis drug-induced liver injury (ATDILI):A pre-clinical studySumbul ut teeb, Afsanteen, Majeeth, Gul surkh, Revand chini, Mastagi, Filfil siyah
16Assessment on the modulation of Anticancer activity of Standard Cancer Drugs by Nutraceuticals and Unani drug in colorectal cancer”Majun Sangdana Murgh, Coriandrum sativum and Trachyspermm ammi
17Unravelling the cardioprotective mechanism of Khamira Abresham Hakim Arshad Wala using in-silico, in-vitro and in-vivo (New Zealand Rabbit) system: A step towards planning a clinical trial with Unani formulation for cardioprotectionFruit rind of Halela Zard, Fruit rind of Halela Kabuli, Halela Siyah, Fruit rind of BaleIa, Drv fruit of Amla, Gule Surkh, Anisoon, Gule Gaozaban, Kishneez Khushk, UNIM CP-1 (Majoon)
18Redesigning & Evaluation of Antifungal potential and Mechanism of action of Marham Hina, a Unani pharmacopoeial formulation against Resistant Candida stains and Dermatophytes”Marham Hina
19Preparation of sugar-free Khamira-e-Gaozaban Sada (sf KGS) and it’s comparison with the Unani drug (KGS) for their immunomodulatory potential against the in vivo model of maniac phase of bipolar disorder (BD)Khamira-e- Gaozaban Sada (sf KGS) (lab prepared sugar free and marketed)
20Effect of Unani Formulations against Mitochondrial Mediated Cellular Mechanisms: A strategy to combat Alzheimer’s DiseaseMajun Falsafa, Majoon-e-Bhrami, Majoon-e-Baladur
21Formulation, Development and Preclinical evaluation of novel Unani dispersible tablets for Immunomodulatory activity and as adjuvant to Anticancer therapyZanjabeel (Sonth), Zard Chob/Aamba Haldi, Asl-ul-Soos, Filfil Siyah, Hulba, Samagh-e- Arabi, Rewand Chini
22Evaluation of Unani formulation-Harira for improving mental retardation and exploration of underlying molecular mechanisms using animal modelHarira
23Development and Evaluation of New Intranasal Nano formulation of Anti-epileptic Unani Medicinal HerbsOod saleeb, Ustukhudoos, Habb-e-balsan
24To Perform Shelf Life studies and Animal safety Studies of selected Unani Formulations as per ICH/OECD Guidelines”Majoon Suparipak, Khameera Gaozaban ambri, Majoon Suranjan, Khameera Aabresham Sada, Majoon Chobchini
25Preclinical and clinical studies to evaluate the safety and efficacy of topical Unani formulation in DermatophytosisUnani paste (Kibreet, Suhaga, Naushadar, AhakeAabRase eda, Seer, Mazu
26Local application of Novel Unani gel/Paste formulation for medical management of Oral submucous fibrosis (OSF): A randomized controlled clinical trialAlsi, Rub-us- SooSSiyah, FilfilSiyah, Gond Keekar, Magz-e-Badam Shireen, Maghz-e- Akhrot
27Pharmacokinetic and pharmacodynamics studies of Habb e Asgand- a clinically used anti-arthritic Unani formulationHabb e Asgand
28Preclinical and Immunotherapeutic assessment of Majoon Najah an Unani Formulation in Cervical CarcinomaMajoon Najah
29Study and validation of the anticancer potential of prominent Unani medicines Arq Makoh and Arq Kasni and their nano formulations against liver carcinomaArq Makoh and Arq Kasni
30A randomised Controlled trial comparing Unani medicine plus standard of care vs Standard of care in reducing exacerbations in COPD patientsSufoof Kakra Singhi (Kakrasingi, Zanjabeel, Filfil-e-daraz)
31Evaluation of Unani Polyherbal formulations, acting as Muqawwi Dimagh for their potential to inhibit Acetylcholinesterase and ameliorate Beta-amyloid toxicityMajoon-e-Bolas, Majoon-e-Baladur, Majoon-e-Falasifa
32Design, Development and Evaluation of Novel Immunodulatory RTD (Ready to Dispense) formulations UNIM 2020A and UNIM 2020BUNIM 2020A and UNIM 2020B
33Development of chemical profile and identification of bioactive & chemical markers for authentication and elite identification of the selected Unani herbal drugsUnnab, Sapistan, Behidana
34Evaluation of Unani Drug on FoxP3 expressing regulatory T Cells in the modulation of rheumatoid arthritisMajun Jograj Gugal, Majun Suranjan, Majun Chob Chini Ba Nuskha Kalan
35Effect of Selected Unani formulation on oxidative stress in patients with type 2 diabetes mellitus a randomized double-blind placebo controlled clinical trialQurs-e-Ziabetus Sada
36Design and Development of a Standardized Dry and Wet Cupping Therapy Device: An Efficient way to perform Cupping TherapyAutomated Design of Cupping Device
37Evaluation of a Unani Polyherbal formulation, acting as a brain tonic, and its constituents for potential Anti-Alzheimer activityJawarish Shahi
38Molecular mechanisms and effect of Cardioprotective Unani drugs Khamira Abresham, Dawa-ul-Misk Motadil and Khamira Gawzaban on Nitric Oxide (NO) production, uncoupling and reactive oxygen species (ROS) generation in AtherosclerosisKhamira Abresham, Dawa-ul-Misk Motadil and Khamira Gawzaban
39Exploring the therapeutic potential of Majoon Ushba, and Unani Medicine against psoriasis (Dau-S-Sadaf) with reference to IL-17 acytokine signallingMajoon Ushba, Arq murakkab mussaffi khoon
40Investigate the Therapeutic and Chemo-Sensitizing Efficacy of Unani Pharmacopoeial formulation Dawa-ul-Kurkum on Head and Neck Squamous Cell CarcinomaDawa-ul-Kurkum
41Colon targeting of Unani Medicine via gum (polysaccharide) based oral formulations for effective treatment of irritable bowel syndrome: Clinical Intervention by Gamma ScintigraphyJawarish Shahi
42To investigate the Pharmacological effect of certain Unani formulations in a Preclinical animal model of Polycystic Ovary SyndromeArq-e-qasni, Arq-e-mako, Majoon Dabid-ul-ward
43Design and Development of Sharbat Ahmad Shahi in to Tablet alongwith its Physico-pharmaceutical and Pharmacological evaluationSharbat Ahmad Shahi
44Assessment of the effect of Unani formulation loaded nanoparticle tablets against Streptozotocin-induced DiabetesQurs Gulnar nanoparticles
45Preclinical and clinical validation of safety and efficacy of traditional Unani formulation Sharbath Mundi pertaining to its hepatoprotective effectSharbath Mundi
46Phytochemical Profiling, Assessment of Safety, and Validation of Anti-amnestic Effect of the Majoon Boolis: a Preclinical InvestigationMajoon Boolis
47Anti-diabetic and Immune-modulatory effect of Unani formulation “Safuf-i-Dhayabitus’Safuf-i-Dhayabitus’
48Studies on Evaluating the Anti-Fibrotic Potential of a Unani Formulation (Majusi Formula)Majusi Formula
49Effect of Unani drugs on the transgenic drosophila model flies of Parkinson’s diseaseKhamira Gawzaban Ambari Jadwar Ood Saleeb vala
50Structural characterization, pharmacokinetics, pharmacodynamic and herb-drug interactions of major constituents of compound Unani formulation for diabetesCompound Unani formulation (CUF)
51Evaluation of safety and efficacy of Unani Pharmacopeial formulation(s) as a therapeutic adjuvant to antiepileptic drugs in drug resistant epilepsyKhamira-i Gāozaban Ambari Jadwar ood Salib Wala and Majoon-e Najah
52Anticancer efficacy and molecular basis of Dawa-ul-Kurkum on the tumorigenesis of pancreatic ductal adenocarcinomaDawa-ul-Kurkum
53Novel Unani Medicine infused Organic Oil based in-soles for diabetic foot careZaroor-e-Qawi
54Evaluation of Munḍij-i-Balgham and Mushil-i-Balgham Unani Formulations in Cerebral Ischemic StrokeMä’ al-‘Asal, Munḍij-i-Balgham (Aslussoos, Badyan, Beekhe Badyan, Ustukhuddoos, Anisoon, Tukhme Karafs, Ood Saleeb, Beekhe Izkhar, Barge Gaozaban), Mushil-i-Balgham (Ustukhuddoos, Barge Sana, Turbud, Maghz Fuloos Khayar Shambar, Raughane Zard)
55Gut microbiota heterogeneity in association with Obesity and T2DM and the intervention of Unani medicinal drug Qurse-Ziabetus on gut microbiotaQurse-Ziabetus Khaas and Safoof Ziabetes
56Harnessing Unani Medicines in an Emulgel Formulation for Managing Imiquimod-Induced Human Plaque-Type Psoriasis in Pre-Clinical TestingUNIM-402 loaded emulgel formulation
57Development of a DNA barcode library of plant origin single drugs of Unani Pharmacopoeia for authentication of plant species used in Unani system of medicineList of 100 medicinal plants
58Establishment of Quality Standards, In vivo Anxiolytic Activity and Formulation Development of Natural Sweetener based Syrup of some Unani DrugsNovel Formulation
59Formulation and Evaluation of Nanostructure Lipid Carrier Based Transdermal Gel for Polycystic Ovary Syndrome (PCOS) and Associated ComplicationsHabb-e-mudir, Majoon Muqawwi Rahem and Majoon-e- Dabidul-ward
60Standardization and validation of Khamira Abresham & Khamira Marwareed for Isoprotrenol induced Myocardial Infarction via eNOS and ROS generation through Nano Drug delivery SystemKhamira Abresham & KhamiraMarwareed
61Exploring the anti-cancer potential of a Unani Drug toot-e-siyah (Morus nigra) on mice modelstoot-e-siyah (Morusnigra)
62Pharmacological and Molecular Investigations of Qurs Zarishk Haar in the Model of Alcohol-Induced HepatitisQurs Zarishk Haar
63Evaluation of the Osteogenic potential and safety of Unani Formulations Majun Falasifa and Kushta-e- Gaudanti in Osteopenia Model.Majun Falasifa and Kushta-e- Gaudanti
64A preliminary randomized controlled trial to test the safety & efficacy of Unani formulation in patients suffering from Ulcerative colitisBihidāna (Cydonia oblonga Mill. seeds)
65Exploration of Combinatorial Therapy of Unani Drugs Irsa, Hasha, and Anisun as Multitarget Approach for PCOS and Associated Metabolic Disorders in Pre-Clinical ModelIrsa, Hasha, and Anisun
66Effect of Unani Formulations (Dawa-e-Sahaj, Jawarish-e-Mastagi, Qurs-e-Gul) for the Inhibition of NLRP3 inflammasome activation: A strategy to mitigate inflammation for the therapy of Ulcerative Colitis disease.Dawa-e-Sahaj, Jawarish-e-Mastagi, Qurs-e-Gul
67Harnessing Classical Unani Medicine to Combat Aging-associated Muscle Wasting: an in silico, in vitro, and in vivo approachMajoon-e-Araad Khurma, Laboob-e-Sagheer, Majoon-e Falasafa, Khamira Gawzaban Sada, Khamira Abresham Sada and Khamira Marwarid
Newly Initiated projects
S.No Project Title Unani Formulation
1 Evaluation of Unani Formulations Habb-e-Azaraqi, and Habb-e-Aasab in Experimental Models of Neuropathic Pain: Targeting Mitochondrial Dysfunction and Neuroinflammation Habb-e-Azaraqi and Habb-e-Aasab
2 Deciphering the Therapeutic Potential of Unani Formulation on Age-Related Macular Degeneration: Elucidating Mechanistic Insights Incorporating Multi- Omics Approach Habb-e-Jadwar
3 “Development of Unani formulations for effective therapy against Triple Breast Cancer” Halela Siyah, Aftimoon, Bisfayej, Ustukhudoos, Kutki, Ghariqoon and Namak Siyah
4 Therapeutic potential of selected Unani formulations against Metabolic Dysfunction – Associated Steatohepatitis (MASH): In silico, In vitro and In vivo evaluation Hab-e- Kabid Naushadri, Qurs afsanteen,
5 Evaluation of Khamira-e-Zahar Mohra for mitigating Doxorubicin and Isoprenaline-induced cardiotoxicity in rodents via biochemical and histopathological markers Khamira-e-Zahar Mohra
6 Establishing Scientific Validation of “Itrifal Sanai” for its medicinal use in the management of stress and depressive disorders Itrīfal Sanai,
7 In Vitro, In Vivo And Ex Vivo, Investigations Of Unani Drug “Khamira e Sandal Sada” On Modulating Epigenetic Mechanism Of Inflammatory Genes Involved In Atherosclerosis Disease Aggravation Khamira e sandal Sada
8 Scientific Validation and Mechanistic Insights into Unani Remedies for Psoriasis: Focus on NF-κB, IL-23/Th17 Axis, and keratinocyte dysregulation Formulation 401 and Formulation 402
9 Role of poly-herbal formulation on the bone’s ultrastructural, metabolic and biomechanical changes in Diabetic BALB/c mice Unani Formulation
10 Pharmacological evaluation of Khamira Sandal Sada Tablets in Experimental model of Heart Faliure Khamira Sandal Sada
11 Efficacy of a polyherbal formulation Habbe Suranjan, integrating inflammatory biomarkers and targeted metabolomics in patients with stable coronary artery disease on standard therapy: a randomized, open-label study Habb -E- Suranjan
12 Comparitive study of Sugar free formulation of Jawarish Zarooni Sada with its traditional forumulation for the treatment of Diabetic Nephropathy Jawarish Zarooni Sada
13 Pharmaco therapeutic screening of two dosage forms of Majoon e Brahmi in cognitive disorders of children Majoon e Brahmi
14 Herbo-Pharmacological insights into Majun-e-Khadar in Alzheimer’s and Parkinson’s Disease : modulating PI3k/Akt/GSK-3B signalling pathway” Majoon-e-Khadar
15 Evaluation of “Therapeutic Potential of Unani Formulation in the Management of Knee Osteoarthritis in a Tertiary Care Hospital” Unani Formulation
16 Deep Learning based Urine Examination for Color, Precipitation, Viscosity, and Froth from Urine Images in Unani Healthcare AI Related
17 Screening of Unani medicinal plants/formulations for antimicrobial potential against multidrug resistant uropathogenic bacteria using AI/ML assisted in-silico and experimental approaches. Unani Formulation
18 Mechanistic exploration of Unani formulation (oral tablet of Majoon Najah) on cognitive deficits through cAMP/PKA/CREB mediated synaptic remodeling in rat model of vascular dementia Majoon Najah
19 Integrated Study of Psoriasis Pathogenesis and Therapeutic Evaluation of Unani Formulations Using 2D Cell Culture and Mouse Model Joshanda Aftimoon
20 Unlocking the anticancer efficacy of Safoof-e-Saba’a, a Unani Pharmacopoeial formulation: An integrated analysis on Stage I & II Breast Cancer with in-vitro, in-vivo and in-silico analysis Safoof-e-Saba’a
21 Anti-Anemic activity of Sharbat-e-Faulad with improved dosage form Sharbat-e-Faulad